If you have an LDL level of 130 mg/dL or greater, you will generally need to take an LDL-lowering medicine. If your LDL level is 100 to 129 mg/dL, your doctor will consider all the facts of your case in deciding whether to prescribe medication for further LDL lowering or for high triglycerides and/or low HDL if they are present. If you have been hospitalized for a heart attack, your doctor will likely start you on a medication at discharge if your LDL-cholesterol is 130 mg/dL or greater. If your LDL-cholesterol is between 100 and 129 mg/dL during your hospitalization, your doctor may choose to start you on an LDL-lowering medication before you are discharged. Also, if your LDL-cholesterol is far above the goal level of less than 100 mg/dL when first measured, your doctor may choose to start a cholesterol-lowering medication together with diet and physical activity right from the beginning of treatment. If your doctor prescribes medicine, you also will need to:

Follow your cholesterol-lowering diet.
Be more physically active.
Lose weight if overweight.
Control all of your other heart disease risk factors, including smoking, high blood pressure, and diabetes.
Taking all these steps together may lessen the amount of medicine you need or make the medicine work better--and that reduces your risk for a heart attack. The following is a description of cholesterol-lowering medicines.

Statins
Bile Acid Sequestrants
Nicotinic Acid
Fibrates

Other Drugs:

Hormone Replacement Therapy
Combination Drug Therapy